Cubic inches are your friend. The more you have, the less you have to push the valvetrain and rpm. If you can find a good 540 or 572 race motor and put a set of dished pistons in it and a mild roller cam, provided you have the budget, you could run a lot less rear gear and still meet your goal. That is what i am considering doing with my 528 when the day comes to retire from the track.
I would go 11.00 compression, 572 cubes, minimum head would be a 440-1 ported, dominater carb on a single plane intake, 2 1/8 headers, converter, tires and gears dependant on wheel well space. Biggest bias type slick you can run, gear it for 6500 rpm at 135 mph. Torqueflite with about 5,000 stall. This will allow pumpgas, and live a long happy life.
If budget dictates a stock block, i would go 400 block, 512 cubes, same top end, and high compression and run e85 to meet the goal easily. Use more rpm, but still be carefull on cam choice. You want something that will live a long time.