OK. I'll try to help.
The warm up issue is due to choke setup, or lack of it.

What Holley List number?
(That's the number stamped on the Choke tower if there is one).

The timing is OK starting point.
What is the rpm at idle (when warmed up)?

It would be good to measure the timing curve (with no vacuum advance).

When you write "makes a detonation", do you mean loud Bang? And was it in the exhaust or intake/carb?