The TH400 + GV cannot have a locking torque converter, 4L80E can (but $$$ if you need WOT locked).
Both require D/S mods; shorter makes the angle worse but the D/S will be stronger.
4L80E may need tunnel bashing due to large diameter far back?
Both require serious aftermarket parts for your power level.
GV adds more length, make a worse D/S angle.
4L80E controls are more expensive but useful.
4L80E has slightly taller O/D at .75:1, GV is .78:1, otherwise the ratios match.
GV is far more expensive (than the extra cost of 4L80E over TH400).
See my table of O/D transmissions here:
http://victorylibrary.com/mopar/aod.htmDid you know there is a 6L80E...?