Basically if you need more than studs and aluminum caps...you probably need an aftermarket block.  It can't hurt, but I personally wouldn't bother. I'd use aluminum caps with studs and run it. I'm going to test the limits soon of a stock block 440 w/ a stock crank and caps, ARP bolts. The motor is in the 680-700 hp range. Once I get it dialed in N/A, I'll turn on the plate.
CHIP
'70 hemicuda, 575" Hemi, 727, Dana 60
'69 road runner, 440-6, 4 speed, Dana 60
'71 Demon 340, no drivetrain, on blocks behind the barn
'73 Chrysler New Yorker, 440, 727, 8.75
'90 Chevy 454SS Silverado, 476" BBC, TH400, 14 bolt
'06 GMC 2500HD LBZ Duramax
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