Yup...I have big tires....And I am slow....Oooh, and I won the Modified Gasser championship last year.
So if your a bracket racer, it may slow you down if they are bigger than you need, but the track is not always perfect either.
What I don't have to do is adjust the suspension for evey little track imperfection or changing conditions...I do make changes to it, but generally once its set-up, it hooks.
I drove a 600hp small tire car a couple years ago....Doing a Ssss down the track is not my idea of racing. Nor did I feel very safe staying in the throttle....