Call the experts and see what they recommend. You will need an idea of what the heads flow, and the intake port cross section area (no reason to over cam what the heads won't flow.)
If the car is setup with alot of gear and converter, you can use a larger cam that has more power in a narrow power band. If the car is more street/strip setup, then you need a wider power band / smaller cam. The 0.050" numbers are just a general reference point when comparing cam size, but it tells nothing of the rate of lift (two cams with the same 0.050" numbers can be quite different at 0.200+" lobe lift.) Your rocker arm ratio needs to be taken into account too. For our older Mopar engines, usually 1.6:1 ratio is normal, higher ratios are fairly uncommon because of cost.