Excluding your Budget ( not mentioned), your goals are very realistic and easily attainable with a big or small block. From a $ stand point consider a later Mopar such as a Cordoba or Volare / Aspen as they are still $ friendly to purchase and not your run of the mill Mopar that you usually see at the track. I initially drove my late B to the track ( 3900 lb car ) with a warmed up original 360, original 727 and 9 1/4 diff and ran high 12's. 11.80's with a very mild 408. It was still very streetable ( my interpretation ) and very $ friendly. When working out your goals, consider where you want to be with it - say 5-6 years from now. It will have an impact on how you start. I bring this up because most who start these projects come to a street / race crossroad decision at some future point in time. Have fun.

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