Not all that hard to do, really: back in the mid-70s my Duster (the Ed Hamburger car) was the first SS/IA car in the 10s and had the NHRA record for a while.
Mid-late '90s with a 358" 340, iron W2s, Crane flat tappet, basic 904, 5.38 gear & 13x31 tire, modified SS springs, I was running 10.50s in decent air.
Now 368" R1 block, Batten W2s, Comp roller, 6000 stall, otherwise pretty much the same, low 10s @ 3500' DA with an 850 Holley and no real tuning, through race bullet mufflers.
By today's standards, nothing really trick: Jack Arnew control arms and a couple of old SS tricks is all. Did have to add wheelie bars after a 300' ride on the rear bumper, though.