If I were building an engine (race and high power street) for Denver or any high altitude only street use such as Flagstaff AZ I would certainly add a couple points of compression ratio over the usual, it really helps when the air is thin.

I re-read the o.p. where it was stated the heads have a mild non-professional port job, to me that indicates the flow is likely 250 or under, and compared to the Victors at 310-320 it seems there should be quite a bit left on the table.

Flow numbers aside, for a super gas level engine I believe the larger cross section max-wedge size intake tract is better. I don't have any real experience with the Victors, is the port between the 2 versions the same except the standard port is necked down at the manifold area? I suspect that is the case after looking at the published port volumes. If so, opening them up (assuming the heads are "standard" port openings) and using a different intake manifold with larger runners could really wake it up.