2001 jeep Grand Cherokee radiator tank blow out from the top hose inlet down what would cause this?? beside being old??

Years of use can weaken the radiator, sure. The one thing that can blow out a radiator quickly is a blown head gasket! The sudden introduction of compression pressure into the cooling system can overwhelm the aged radiator seams and cause a blowout as you have experienced. I sure hope its just a worn out radiator though. Good luck.

My 1997 Jeep did the same thing just as i had parked at a drive-in embarrasing as it was it seems that plastic tank was weak. A new one was only $88 and they had it in stock .

is it the straight six?

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Engines installed in 1999 Grand Cherokees carried the PowerTech name, which had been used intermittently in prior years and on other Chrysler truck and SUV engines. The name was subsequently passed on to 4.0s in the other Jeep models that used the engine, the Cherokee and Wrangler. The cylinder head was again changed for the 2000 model year to a lower flowing, more emissions-friendly design. This head was designated as "0331" in the casting number. These heads are prone to cracking and causing coolant to contaminate the oil, resulting in catastrophic engine failure.

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amc six

4.7 I forgot to include that sorry!