It also depends on how you are jetted originally!
Installing an open spacer can theoretically require more jetting because of more intake volume and less signal to the carb. However, if you are jetted optimally or a little lean, the car can slow down. If you are jetted rich to begin with, it can pick up!
Same thing with the accellerator pump circuit for the same reasons.
Jet for MPH and experiment with pump cams and squirters for 60' times. Sometimes a rich accellerator pump shot can partially mask lean jetting and rich jetting can mask a lean pump circuit. It ain't always easy.