In 2013, the main difference was the front suspension. The 2500 had 4 link, 3500 used radius arms. For 2014, both 2500 and 3500 have radius arm front suspension, but the 2500 gets 5 link and coils in the rear while the 3500 retains the leaf springs. IMO, the radius arm front suspension is a much better design than the 4/5 link.
For the gas trucks up through 2013, the 10.5" AAM rear axle is used (11.5" for diesel). In 2014, all HD trucks use 11.5", gas or diesel.
Ball joints are an issue, and I've seen gas trucks with prematurely worn ball joints as well. Seems like 60-80,000 is the range that most truck need ball joints, depending on useage. You can replace with Moog for a slight upgrade, or go to the extreme duty pieces from Carli suspension. They're supposed to be very good, but they also cost $800 for the set.