When or does less lifter weight have greater advantage vs using larger lifter wheel diameter by having an advantage with a larger diameter lifter?

"Hyd" normally means limited rpm peak, so a lighter lifter would seem to be an advantage, but a larger diameter (heavier) lifter with its larger wheel seems to have its own pluses. My application is road race/track car, no competition. Its got a 4.25" crank, so high RPM is not a goal. Current SB motor under construction has .842" lifter size bores, 50mm? cam. I will be using a bushed/non needle roller Hyd lifter. Not sure 100% they can be opened up yet anyway, or the meat of this question, is it worth it, and why?

Reality check, that half the population is smarter then 50% of the people and it's a constantly contested fact.