Tune the idle circuits first, all eight of them
I would use the power valves for part throttle cruising
Make sure your fuel system will keep the carbs. full of fuel at WOT
If you can't jet the carbs up enough(richer) to slow the car down in the 1/4 mile you don't have enough fuel volume
As far as adjusting the idle circuits on multiple carbs. I have had to screw them in from 1/4 to 1/2 turn out from bottomed to get the idle circuits lean enough to not foul the plugs
All the rest is basic carb tuning, squirters, primary and secondary jetting, needle and seat size needed and all the rest
Have fun, let us know how it goes