On the cam, it depends on the rest of the combo... and how you like the one you have. Compression, intake/carb, exhaust, rear gear ratio and tire diameter. How does it run with the current cam? In general, cam and springs need to be matched so cam change may require springs depending on what you have to start with.

On the Champion rad, I've never run one but they are pretty poplar on brand F PU's. Is the current radiator getting feeble?

If it runs/cools OK now, those upgrades sound like a lot of money and work for moderate gain.