Hi Anthony. That cam is far too small for those cubes. I have a 493ci Stroker. I use "Diamond Piston" part#52415 which has an effective dish of -12:5cc. I have a deck clearence of 2 thou; & using Comp Cams 294S which is 248@050" & with the cam installed straight-up, has a cranking pressure of 185 lbs. On pump gas this is close to as much pressure that you want to go.
I use Stealth Heads(standard)it idles at 800rpm & with 2:75 gears in an Aussie Charger with myself & fuel weighs in at near 4000lbs, with 4-speed New-Process does 12:00-12:30@ 117-118mph in the 1/4 & 92mph at the 1/8 mile mark.
I also get 17mpg Imperial(approx 15US). 2260 revs @ 62mph.
I believe you will have regrets with a cam that small. It is even small in a 440 so it will just starve a 493ci.
Mike in New Zealand