Here's my combo. I'm not saying that it is the best, but it is what I have.

1978 W200
4 speed manual with 4.10's
33" BFG's

1977 motor home 440 (.030 over)
Stock valve job on factory motor home heads
Speed Pro 9.0 to 1 cast pistons
Rebuilt stock bottom end (cast crank)
Lunati Voodoo 60303LK cam Voodoo Cam
Edelbrock Performer RPM intake
Holley 750 CFM vacuum secondary
Heddman Headers

I just returned from a long trip from southern Virginia to pick up a car just north of NYC . The engine ran GREAT. Super amounts of power. I never had to douwnshift once. Not even on any of the long mountians through upper PA on I-81. I was literally passing folks going up the hills with a '69 Super Bee on my trailer.

But..... The gas mileage was crazy bad. I never broke 7 MPG (even with the empty trailer).

But..... It had lots of power!

Stan