I used to drive from AZ. to MI. all the time in old musclecars from 1984-1992. Change the oil, make sure the brakes were good & the radiator full & hit the road. Oh - I would normally be towbarring as well. Never had anything that started out roadworthy not be able to make it. Minor stuff, but nothing other than an overheat or small electrical issue like a loose wire. We did have a '69 Super Bee fail a fuel pump in Dallas in an absolute downpour - that was fun!