There are "Destroke" kits out there for the 6.0 trucks. It's a whole kit to swap in a 5.9 cummins. That should be a clue to the 6.0's legacy.
I live on the main route in/out of Myrtle Beach, SC. I've seen a LOT of older Ford trucks pulling big camper trailers that sounded different, lol.

There's good and bad in every one of the diesels. Some hate the '98.5-'02 Cummins b/c of the VP44 pumps. The early '01-'04 LB7 Duramax trucks are bad for injectors and head gaskets also.


CHIP
'70 hemicuda, 575" Hemi, 727, Dana 60
'69 road runner, 440-6, 18 spline 4 speed, Dana 60
'71 Demon, 340, low gear 904, 8.75
'73 Chrysler New Yorker, 440, 727, 8.75
'90 Chevy 454SS Silverado, 476" BBC, TH400, 14 bolt
'06 GMC 2500HD LBZ Duramax