In the early 2000s Chrysler used as OEM spark plugs Champion “Double Platinum” that have two tiny alloy discs per spark plug.

On the original OEM plugs and a replacement set, one or more these tiny alloy discs broke loose on my Mom’s 2005 3.3 V6 causing misfires.
These Champions were supposed to last +75,000 miles.

It is really hard to spot the missing disc because even when gone there is a circular weld mark.

A KAL 2969 computerized spark plug analyzer could not reliably spot the misfiring plugs, perhaps because of the “wasted spark” ignition system.

Sandblasting a used spark plug in my opinion could easily knock them off.

Maybe blast with baking soda or dry ice?

I switched to NGK Iridium tip spark plugs and the engine ran noticeably better all around, especially climbing steep Interstate grades.
No problems since.