I wouldn't, and don't ,trust any software formulas on predicting detonation on any Hi Po pump gas motor To many variables like fuel quality, current air density, spark plug heat range and so on
I do start off on the safe side on total ignition timing and spark plug heat range, colder is far better than a tad to hot on the spark plug heat ranges IMO. I'll drive and tune the carb. on the light part throttle cruise and idle mixtures first and then step up to the higher RPM on the primary only cruise to get it where I like it (I like lean, 14.8+ AFR) and then tune for WOT throttle last.
I will find out where the edge of detonation is on both the AFR, timing, gasoline and spark plug heat range and record the weather and all the tune up information