Yes it can be done. There's an old thread on here somewhere on how to do it. I think Petty did it back in the day too. Last fall when Jegs had hemi blocks listed I ordered one to do this exact thing. The Jegs block never came through so........

edit found it,
https://board.moparts.org/ubbthreads/ubbthreads.php/topics/1578095/wedge-head-on-hemi-block.html