As stated above, cubic inches are good friends for this accomplishment. There are guys running as quick as 9.40's in a street car with only 528 cubes. I have not gone that fast with my 605........And for arguments sake, which block are we talking about?

The standard is 572 these days. There are a lot of nice rotating assemblies for this size engine. I have a 605 and it pushes the rod pin up further into the piston, probably as far as you can go. This makes the skirt pretty short and will give you some scuffing of the walls over time. So I would recommend the 572 square 4.5 x 4.5 engine as the best all around size.

Me personally, would love to see someone come up with a hemi and wedge option in the future that would allow us to go well beyond some day.

https://www.youtube.com/watch?v=8LMsBR1dsAs