Dave, whatever you do just make sure you have a spare full bottle! They have a bad way of being empty at all the wrong times [don't ask me how I know]
I switched my dragster to electric shift just for that reason. co2 can be tricky and likes to leak so I shut the bottle off after each pass. Single guage regulator is fine, I just put one in the digger. You do have to attach a guage to adjust line pressure then your done. I replace my bottle when psi drops below 500 on a warm day.