Too much pressure

how much HP are you looking/expecting to make and what kind of RPM are you wanting to turn?

For a non mega-block shortblock app even with a girdle and/or good caps I'd try to stay around the 680-720HP PEAK range and with good heads you don't need that much cam to get there, I don't know the whole combo you are planning but remember the bigger the cam the higher RPM the torque/power peaks will be which means the stress levels on the block raise proportionally. A well machined low deck can handle more power but even still the heavier the car the more load you're putting on it if you want it to last.

Yuo want power and reliability but when you push too high it's tough to get both...you'll going big with the cam so that means you gotta be willing to drop the coin on the valvetrain....I consider that kind of build a time-bomb and if I know ther's that kind of "big power but skimping on the good stuff" in the other lane....I wouldnn't want to stage next to them....Ex: there's hundreds of 500+hp 5.0's out there that won't drop the small coin for c-clip eliminators in the rear-end...can't tell you how many times I've seen an axle fly out of a 5.0 and the car wind up in the other guy's lane!!

Don't mean to sound harsh but I'd like you to think that one over cause with roller motors all bets are off what happens to your motor (and your car) if something internal lets loose. Don't skimp...i think 70Blackfish is selling a set of offset T&D's with roller fulcrums on Moparts Racing parts right now.