I prefer the wheel disc to be centered in the rim for strength. In other words in a rim that is 10" wide, I would like to see a 5" back spacing. In the real world it probably does not make any difference at all but it could. I have seen a lot of bent aftermarket wheels

1986 Dodge Ramcharger 440 2wd, Bracket Racer Under Construction
1998 Ram 2500 QuadCab, new daily driver.
2008 Honda Element
2014 Carry-On 7x14 Cargo Trailer