My 440 has the 4.25" stroke crank and 7.1" rods (440 Source kit), and the only clearance grinding required was the oil tube boss. I used the 17cc dish pistons 0.030" oversize, so the engine is really 505", not 512". I threw some mild ported stealth heads on it so compression is about 10.3:1.
This was built for the street, Comp XR296HR cam (really mild in this size engine, but idles at 1,000 RPM with a nice sound) 236/242 @ 0.050 duration. I put 3.54:1 gears and an overdrive 5-speed transmission in the car. 1,500 RPM in OD, is 51 MPH, and I don't need to down shift to accelerate.