Not apples to apples but I have a 427" (4.04 x 4.17) stroker SB ford Windsor in a Cobra replica.

The heads flow about 250 @.400 lift and just over 280 at .500 and with a ported victor jr, 800 Edelbrock AVS and a Comp XE 240/246@.050 .542/.542 lift (1.6 rockers) and 1 7/8" headers the 10.25:1 motor made 511 at 5300 and It'll rev to 6000 easy (real easy in a 2450 pound car, lol) and has torque in 5th gear (3.50 gears with a .68 O/D) to take wot and pull hard from only 1600-1800 rpm (highway speed)

My point is if you have really good head flow, a big stroke small block will easily duplicate the power and torque of a big block, and you don't really need a lot of cam to do it. IMO too many people overcam the big stroke small blocks and standard port big blocks and wind up side stepping the sweetest part of the torque curves for those combos in the process,in my case I only wanted to duplicate the power/torque of a 'real' 427 FE and I think I nailed it in terms of driving fun big block 'feel' (face distorting torque at all engine speeds) all in a package that's 150 pounds lighter than the big block.

So good heads can do a Lot with even a comparatively small cam, with a big stroke your piston speed really doesn't favor turning it much more than 6000 or so anyway, for peak (drag race) power your better with a smaller 3.79-4.00 stroke and just up the cam and gearing. But the long arm does have a place and if done right, it's a really fun motor combination.

I'm working up a 440" 360 with a 4.25 stroke and ported W2's with a tunnel ram, ought to be really fun but I won't (want or NEED) to spin it up to tight to do it