is the vehicle a EFI vehicle? or are you swapping it into an old ride?

the only problems I see you having, is that the manifold is designed to be "dry" the stock manifold has a large open plenum, with runners that wrap up and around the intake. think dual carb, cross ram intake runner length, but wrapped up into a barrel shape. I don't know that atomized fuel will flow through that very well.

aside from that, if it's a computer controlled vehicle, it won't like that the fuel injectors don't respond anymore (unless you leave them installed and hooked up so the computer can see them "working") and the computer won't be happy that it can't see the MAP, TPS, IAC.