I did it to the hot rod. You will have to modify the transmission crossmember a wee bit. I turned mine around backward for the 4 speed I dropped in. With the 727 I stuck the tranny mount in the center of the crossmember.
You will need to shorten the drive shaft.

If you have a column shift automatic the exhaust manifold will not fit around the shift brackets on the column under the hood. The column length will be the same.

If using a 4 speed the pivot mount on the frame rail will need to be moved and the linkage modified.

We are brothers and sisters doing time on the planet for better or worse. I'll take the better, if you don't mind.
- Stu Harmon