If you do a cam swap, don't go too crazy. The 6.1 cam seems to be a common swap, anything larger will require some kind of tuner to compensate. Also with the tuners, MDS can be turned off permanently and I believe people are using non MDS lifters in all 16 holes. FWIW the Diablosport Predator tuner has the most and best functions. I would shoot on over to the forums at http://hemitruckclub.com/ Thats probably one of the best tech places for these trucks.