I'm a fan of Engle's hydraulic FT cams - haven't heard of issues like Comp apparently has.
My 406" SB street Duster with AC ran K54 intake lobe (214 @.050, .470 lift) & K56 exhaust (224 & .504) - plenty of vacuum, great throttle response, and sounded meaner than it was.
For my 448" RB street B-body, scaled up to K56 (224/.504) Intake and K58 (230/.520) Exhaust; same effect, though a 4-speed non-AC car.
Can't recall if 110 or 112 LC, though. Worth a call to Engle for their advice.
Johnson EDM lifters in both, zero problems.
406 was iron head @ 9.5:1CR, a bit marginal on octane until I dialed some timing out; 448 had Eddy heads & 10.3 CR, perfectly happy on pump 92.
As stated, CR matters on pump gas street cars; ya need to measure that.

FWIW, K60 is 238/.534.
Those are their older grind #s; their numbering has changed, but last I heard they'll grind whatever they've made in the past.