I've heard and been told no and yes on intercooling so far.
I know some guys who use to run an old style 392 hemi in Top Alcohol dragster, they were using Brad Andersen parts and his help on tuning. They had 12.0 to 1 compression ratio and Brad wanted them to increase it up to 13.+ to 1 ratio on straight methanol with the blowers available back then
I may try it first without an intercooler and monitor the manifold inlet temps and decide from them on adding intercoolers or not
I'm planning on going with really safe set ups to start with on all the tuning and see what it does and look at the plugs and time slips and go from there
I got a lot on my plate to get done before then so I'm in no rush, I'm trying to get everything right before starting hence my question on the compression ratios on E85 now
Thanks to all for your help on this