I need to read more about Hemi builds, but now I'm wondering,
since there is no squish area, do you have to run less
compression ratio than a 572 wedge ? For pump gas that is.

Or if you have the compression on the Hemi, do you also need
more cam duration than the wedge, to bleed off some pressure ?

As an aside, I think that in general, bigger bores are more
detonation sensitive than smaller bores, and a 572 Hemi has a
big bore as well as no squish.