I help a friend w/ his Camaro. 436" sbc, 14.5:1 compression, AFR heads, glide, 9", ladder bars, etc. Makes somewhere around 700 hp.
Ran on alcohol (4150 Demon 825 cfm carb) and ran a best of 5.78 in the 1/8 mile w/ a 1.24 sixty foot at 2900 lbs. Ran this configuration for years.

Switched it to race gas a few years ago (112) and went to a 1050 Dominator...same manifold (Edelbrock Victor 4150) w/ the tall 4500 adapter. Now it's 100 lbs heavier at 3000 lbs and it went a best of 5.93 w/ a 1.27 sixty foot. It lost a noticeable amount of lowend torque and obviously some HP, but never dyno'd either setup.
Knew it would slow down some, but was hoping the Dominator would help not to slow down too much. It has more in it (still needs more tuning), been a long time since the car was run, but it won't run what it did on the alcohol.