I haven't hooked up my A/F sensor yet so no tuning experience with it yet, but basically jet for mph and tune accelerator pump squirters and pump cams for 60'. (I got it to help figure out my new Thermoquad combo, but I ran a Holley for a long time.)

A good baseline for a mostly stock cab is the original jetting with 6-10 bigger jets where you removed the power valve. That depends on the PVCR - the holes under the power valve.