I ran my last Hemi ('06 Durango) over 160k. My current one ('11 Durango) has 150k and I expect to run it to 200+k. Yes, the Hemi's of that vintage have 30k plugs... which go 40-45k with moderate use. I hit the coil on plug connectors with some WD 40 before changing plugs. Then its an hour and a half job done carefully by a novice.

On the engine - besides plugs/oil/filters - I replaced a water pump and fan clutch. Performance and oil consumption were as new at 160k.

If the truck has a 9.25" rear, they are sensitive to leaks. I had a leak and didn't catch it soon enough. Dealer rebuild of the rear hurt a little.

On the Chassis, brake pads and shocks at 100k and new front pads and rotors at 150k. Also a reman steering rack around 130k... may have had something to do with hitting a small surprise snow drift under an overpass at speed in N Dakota. The truck took it OK at the time but that was a very very big bump.