Yes I have ran them. 410 SB, 4spd. Revved it up all day to 7200RPM. They work well. This was with as Solid Flat Tappet though, 262@50 w/.624 Lift. They held the valve adjustment very well, hardly ever needed to adjust them and if so only a few exhaust valves. Was using Manton Ball Cup push Rods, oil thru on LA Heads. Pressureized oil on the ball and cup. Was also running Johnson Oil through EMD Lifters. FWIW