Yes and yes. Occasionally in order to get a motor to idle you have to open the butterflys past the idle transfer slots so now the motor is running (idling) on the primary circuit instead of the idle circuit and any adjustment to the idle screws is pointless. By drilling holes in the butterflys they allow just enough extra air such that the butterflys can now be closed enough that they cover the transfer slots and allow you to tune the idle circuit. A 1/8" hole in each primary blade is a good starting point and it doesn't matter where you drill them as they're only purpose is to bleed air into the motor. If your car idles on the idle circuit there is absolutely no point to drilling the holes.
OK, I follow that. I have an engine with a lopey cam and drilled (not by me) throttle plates that will not idle below 2000 rpm even with the plates fully closed. To me this says too much air is getting through.
I figure I can either take some timing out or close the holes with epoxy.
Question #1 What carburetor(s) are you working with? some have the adjustment on the secondaries while others do not
Question #2 have you verified the timing mark (TDC) on the dampner is is the correct spot?
Question #3. If so to #2, What is your initial and total timing
Question #4 Are you running a vacuum advance?
Question #5 If yes to #3, is is hooked up to ported or manifold vacuum?
Either way disconnect and plug the port until the idle and timing are sorted out.
Question #6 What size are the existing holes?
Next read my post 392117 above
Might also want to read 392125 AND 392126.
You can back the timing off but if the holes are too large you are band aiding the root cause of the issue which has to isolated.
Closing the secondaries a bit can also help but do not close them too far as their purpose is to (bleed) keep fresh fuel in the secondary bowl(s) should they not be used for an extended time.
As far as timing goes, the initial and total will be determined by your combination. As this is an idle issue I would start at ~ 10-12 initial.
Some may argue with the above but it is a starting point to get the idle under control. once that is accomplished
Do the above and report back
You may also as mentioned in 392134 have a Vacuum leak. I would verify the above first. We can then look at a possible vacuum leak