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Re: The official Coronavirus thread [Re: jcc] #2838627
10/29/20 07:19 AM
10/29/20 07:19 AM
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Originally Posted by jcc
Originally Posted by 360view
Covid-19 antibodies last at least 5 months

https://medicalxpress.com/news/2020-10-people-mount-strong-antibody-response.html

Sample quote


"While some reports have come out saying antibodies to this virus go away quickly, we have found just the opposite—that more than 90 percent of people who were mildly or moderately ill produce an antibody response strong enough to neutralize the virus, and the response is maintained for many months," said Florian Krammer, Ph.D., Professor of Vaccinology at the Icahn School of Medicine at Mount Sinai and a senior author of the paper. "Uncovering the robustness of the antibody response to SARS-CoV-2, including its longevity and neutralizing effects, is critically important to enabling us to effectively monitor seroprevalence in communities and to determining the duration and levels of antibody that protect us from reinfection. This is essential for effective vaccine development."

Study findings are based on a dataset of 30,082 individuals, who were screened within the Mount Sinai Health System between March and October, 2020.

End quote


So that begs the question, if a recovered COVID patient donates antibody rich plasma, do the donated antibodies get naturally replaced for the 5? months mentioned above or is the donor now only have say 4 months implied protection?


No.
Donated antibodies in convalescent plasma do not replace themselves inside the patient who got the plasma.

Re: The official Coronavirus thread [Re: 360view] #2838775
10/29/20 01:20 PM
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Early results hint fitness tracker wrist bands might detect Covid-19 infection with 80% accuracy

https://medicalxpress.com/news/2020-10-early-results-trackers-covid-infections.html

Sample quote

In a study that appears today in Nature Medicine, the Scripps Research team reports that wearable devices like Fitbit are capable of identifying cases of COVID-19 by evaluating changes in heart rate, sleep and activity levels, along with self-reported symptom data—and can identify cases with greater success than looking at symptoms alone.
...snip...
For the study, the team used health data from fitness wearables and other devices to identify—with roughly 80% prediction accuracy—whether a person who reported symptoms was likely to have COVID-19. This is a significant improvement from other models that only evaluated self-reported symptoms.

As of June 7, 30,529 individuals had enrolled in the study, with representation from every U.S. state. Of these, 3,811 reported symptoms, 54 tested positive for the coronavirus and 279 tested negative. More sleep and less activity than an individual's normal levels were significant factors in predicting coronavirus infection.

End quote

Re: The official Coronavirus thread [Re: 360view] #2839021
10/29/20 09:21 PM
10/29/20 09:21 PM
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Originally Posted by 360view
Originally Posted by jcc
Originally Posted by 360view
Covid-19 antibodies last at least 5 months

https://medicalxpress.com/news/2020-10-people-mount-strong-antibody-response.html

Sample quote


"While some reports have come out saying antibodies to this virus go away quickly, we have found just the opposite—that more than 90 percent of people who were mildly or moderately ill produce an antibody response strong enough to neutralize the virus, and the response is maintained for many months," said Florian Krammer, Ph.D., Professor of Vaccinology at the Icahn School of Medicine at Mount Sinai and a senior author of the paper. "Uncovering the robustness of the antibody response to SARS-CoV-2, including its longevity and neutralizing effects, is critically important to enabling us to effectively monitor seroprevalence in communities and to determining the duration and levels of antibody that protect us from reinfection. This is essential for effective vaccine development."

Study findings are based on a dataset of 30,082 individuals, who were screened within the Mount Sinai Health System between March and October, 2020.

End quote


So that begs the question, if a recovered COVID patient donates antibody rich plasma, do the donated antibodies get naturally replaced for the 5? months mentioned above or is the donor now only have say 4 months implied protection?


No.
Donated antibodies in convalescent plasma do not replace themselves inside the patient who got the plasma.


That answer is not exactly the question I asked, my original question still stands as I see it.


Reality check, that half the population is smarter then 50% of the people and it's a constantly contested fact.
Re: The official Coronavirus thread [Re: jcc] #2839149
10/30/20 07:08 AM
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In the original patient with Covid
who generously provided convalescent plasma,
that original patient’s specialized B-cells continue to make antibodies for several months,
at least 5 months, probably more.

Re: The official Coronavirus thread [Re: 360view] #2839153
10/30/20 07:17 AM
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High rate of symptomless COVID-19 infection among grocery store workers: says British study

https://medicalxpress.com/news/2020-10-high-symptomless-covid-infection-grocery.html

Sample quote

One in five (21 out of 104) workers tested positive for SARS-CoV-2, indicating a prevalence of 20% at that point in time. This was significantly higher than the prevalence of the infection in the local community at the time: 0.9-1.3%.

Three out of four of those testing positive (76%) had no symptoms. And of those testing positive, most (91%) had a customer facing role compared with 59% of those testing negative.

Workers in customer facing roles were five times more likely to test positive than their colleagues in other types of role, after accounting for potentially influential factors, such as the prevalence of SARS-CoV-2 where they lived. Those in supervisory roles were six times more likely to do so.

End quote

Re: The official Coronavirus thread [Re: 360view] #2839367
10/30/20 04:41 PM
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Already approved nose spray drug Aprotinin may fight Covid

https://medicalxpress.com/news/2020-10-drug-candidate-treatment-covid-.html

Re: The official Coronavirus thread [Re: 360view] #2839370
10/30/20 04:51 PM
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UK research on Covid fatality rate

https://medicalxpress.com/news/2020-10-covid-deaths-infection-fatality-ratio.html

Sample quote

Risk of death from COVID-19 doubles for approximately every eight years of aging.
...snip...
Age-specific IFRs increased from 0.1% and below for individuals under 40 years to greater than 5% among individuals over 80 years

Using these age-specific estimates, the team estimates the overall IFR in a low-income country,
with a population structure skewed towards younger individuals,
can be expected to be approximately 0.23% (95% prediction interval 0.14-0.42).

In contrast, in high income countries,
with a greater concentration of elderly individuals,
the report estimates that the overall IFR can be expected to be approximately 1.15% (95% prediction interval 0.78-1.79).

End quote

Re: The official Coronavirus thread [Re: 360view] #2839447
10/30/20 08:49 PM
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Originally Posted by 360view
In the original patient with Covid
who generously provided convalescent plasma,
that original patient’s specialized B-cells continue to make antibodies for several months,
at least 5 months, probably more.


Thank you, if that is at least a semi universal immune response, that is the answer to my question.


Reality check, that half the population is smarter then 50% of the people and it's a constantly contested fact.
Re: The official Coronavirus thread [Re: 360view] #2839812
10/31/20 04:50 PM
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Computer Artificial Intelligence program claims
83% to 100% success detecting Covid from sound of cough

https://techcrunch.com/2020/10/30/c...as-an-early-warning-system-for-covid-19/

Sample quote

The model seems to have detected subtle patterns in vocal strength, sentiment, lung and respiratory performance, and muscular degradation, to the point where it was able to identify 100% of coughs by asymptomatic COVID-19 carriers and 98.5% of symptomatic ones, with a specificity of 83% and 94% respectively, meaning it doesn’t have large numbers of false positives or negatives.

“We think this shows that the way you produce sound, changes when you have COVID, even if you’re asymptomatic,” said Subirana of the surprising finding. However, he cautioned that although the system was good at detecting non-healthy coughs, it should not be used as a diagnosis tool for people with symptoms but unsure of the underlying cause.

I asked Subirana for a bit more clarity on this point.

“The tool is detecting features that allow it to discriminate the subjects that have COVID from the ones that don’t,” he wrote in an email. “Previous research has shown you can pick up other conditions too. One could design a system that would discriminate between many conditions but our focus was on picking out COVID from the rest.”

End quote

Re: The official Coronavirus thread [Re: 360view] #2839819
10/31/20 05:17 PM
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Face shields worked well at Texas hospital

https://www.medpagetoday.com/meetingcoverage/idweek/89321

Re: The official Coronavirus thread [Re: 360view] #2840061
11/01/20 10:43 AM
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Ride eternal, shiny and chrome
Re: The official Coronavirus thread [Re: 360view] #2840151
11/01/20 01:23 PM
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CDC may allegedly recommend that “people of color” be first in line for Covid-19 vaccine

https://www.businessinsider.com/cdc...19-vaccine-most-vulnerable-first-2020-10

Re: The official Coronavirus thread [Re: 360view] #2840558
11/02/20 09:49 AM
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India and Africa have had lower Deaths per Million from Covid than some other richer continents.
Could this be due to more germ exposure throughout life in India and Africa?

https://news.yahoo.com/coronavirus-indians-more-immune-covid-000412405.html

Re: The official Coronavirus thread [Re: 360view] #2841278
11/03/20 01:54 PM
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Originally Posted by 360view
Danish researchers say they did a careful study about the effectiveness of wearing masks,
but now cannot find a journal “brave enough” to publish it.

https://justthenews.com/politics-po...iple-journals-amid-rumors-it-shows-masks

Sample quote

A 2019 World Health Organization review of pandemic mitigation measures, for instance, found "no evidence" that face coverings helped to stop the spread of influenza.

Whether or not studies on influenza transmission can apply to COVID-19 is unknown; the disease's relatively recent emergence means that scientific studies on it are in short supply. Studies can take many month to secure funding, develop methodologies, carry out experiments, interpret the findings, write a research paper and get it peer-reviewed and published.

To bridge that gap, a team of Danish scientists earlier this year sought to carry out a major randomized controlled trial study to determine how effective masks might be at stopping COVID transmission. The study, begun in April, involved around 6,000 Danish citizens, half of whom wore face coverings during "normal behavior" and the other half of whom went without them.

The study concluded in June. Yet the Copenhagen newspaper Berlingske reported this week that it has been rejected by at least three elite medical journals so far — the Lancet, the New England Journal of Medicine, and JAMA, the Journal of the American Medical Association.

"They all said no," Christian Torp-Pederson, one of the study's researchers, told the Danish newspaper this week. He added that the study's scientists "cannot start discussing what [the journals] are dissatisfied with, because in that case we must also explain what the study showed, and we do not want to discuss that until it is published."

End quote


More studies about masks:

https://swprs.org/face-masks-evidence/

Graphs show before/after mask mandates in USA States

https://thefederalist.com/2020/10/29/these-12-graphs-show-mask-mandates-do-nothing-to-stop-covid/

Re: The official Coronavirus thread [Re: 360view] #2841284
11/03/20 02:17 PM
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Re: The official Coronavirus thread [Re: 360view] #2841344
11/03/20 05:06 PM
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Originally Posted by 360view


I cannot understand why sniffer dogs were not trained up and used sooner,
but then again in the 1990s I met a guy who trained dogs to sniff prostate cancer at the University of North Carolina at Chapel Hill, and despite better than an 80% success rate, after the grant money ran out, nothing further was done.

Re: The official Coronavirus thread [Re: 360view] #2841419
11/03/20 07:43 PM
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2000 person study hints that Flu Vaccine may reduce severe Covid

https://medicalxpress.com/news/2020-11-influenza-vaccination-effect-covid-.html

Sample quote

Ming-Jim Yang, M.D., from the University of Florida in Gainesville, and colleagues conducted a retrospective review involving 2,005 patients older than 18 years of age who tested positive for COVID-19.
Influenza vaccination status and comorbidities were examined.
Severity of disease as reflected by hospitalization and intensive care unit (ICU) admission was examined as the primary outcome.
The association between influenza vaccination status and hospitalization was examined.

The researchers found that compared with those who were vaccinated,
COVID-19-positive patients who had not received the influenza vaccine within the last year had 2.44- and 3.29-fold increased odds of hospitalization and ICU admission, respectively.
The results were adjusted for age, race, gender, hypertension, diabetes, chronic obstructive pulmonary disease, obesity, coronary artery disease, and congestive heart failure.

End quote

Re: The official Coronavirus thread [Re: 360view] #2841775
11/04/20 04:39 PM
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Longer article about vaccine making company Novavax

https://www.sciencemag.org/news/202...y-end-producing-best-coronavirus-vaccine

Sample quote

What a difference a year—and a pandemic—make. Today, Novavax is slated to receive up to $2 billion from the U.S. government and a nonprofit organization to develop and manufacture a coronavirus vaccine. The company’s stock closed at $80.71 per share on 30 October, it has hired more than 300 new employees, and this month it plans to launch a pivotal clinical trial of its coronavirus vaccine in the United States and Mexico. Made by moth cells harnessed to crank out the virus’ spike protein—which the pathogen uses to invade human cells—Novavax’s vaccine outshone major competitors on key measures in monkey and early human tests.

End quote

Re: The official Coronavirus thread [Re: 360view] #2841821
11/04/20 07:03 PM
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Spanish study of 2,159 patients says taking a statin drug reduces the chance of death from Covid-19 by more than 20%

https://medicalxpress.com/news/2020-11-ongoing-treatment-statins-covid-mortality.html

Sample quote

The percentage of patients who died in the group not treated with statins was 25.4%, whereas it was 19.8% among those who were, which is to say, the treatment group had 22% lower mortality. "The data indicate that treatment with statins prevents one in five deaths," indicated Masana. Furthermore, if treatment with this medicine continued during hospitalization, mortality fell by up to 25%, thus preventing one in four deaths.

Consequently, Lluís Masana went on to say that "not only do these findings demonstrate that treatment with statins has no negative on the evolution of COVID-19, they also show that it significantly reduces patient mortality."

End quote

Re: The official Coronavirus thread [Re: 360view] #2841824
11/04/20 07:08 PM
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Finland doing the best against Covid in Europe

https://medicalxpress.com/news/2020-11-finland-europe-quiet-success-covid-.html

Sample quote

But the national character of the Finns, often characterised as reserved and outdoors-loving, may also have played a part.

"In Finnish culture we are not that highly sociable," Hankonen said.

"We like to be on our own and be a bit isolated."

End quote

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