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Re: The official Coronavirus thread [Re: 360view] #2787257
06/19/20 09:26 PM
06/19/20 09:26 PM
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Re: The official Coronavirus thread [Re: 360view] #2787653
06/21/20 08:26 AM
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I personally went and got a MMR vaccine yesterday.
$112 at COSTCO.

Re: The official Coronavirus thread [Re: 360view] #2787937
06/21/20 11:36 PM
06/21/20 11:36 PM
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Originally Posted by 360view



New York and New Jersey sent covid patients there to free up hospital beds. Something like one third to one half of deaths in Jersey happened in nursing homes.


Ride eternal, shiny and chrome
Re: The official Coronavirus thread [Re: DirectSubjection] #2787939
06/21/20 11:38 PM
06/21/20 11:38 PM
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I heard about the potential success of Favipiravir on the radio today - and it already exists so it can be prescribed a lot sooner if it helps

https://www.livemint.com/companies/...ld-to-moderate-covid-11592665273504.html


Ride eternal, shiny and chrome
Re: The official Coronavirus thread [Re: DirectSubjection] #2787965
06/22/20 05:48 AM
06/22/20 05:48 AM
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Originally Posted by DirectSubjection
I heard about the potential success of Favipiravir on the radio today - and it already exists so it can be prescribed a lot sooner if it helps

https://www.livemint.com/companies/...ld-to-moderate-covid-11592665273504.html


Favipiravir
( brand name Avigan in Japan, now Fabiflu in India)
Can cause birth defects in babies whose mothers took it while pregnant
but I cannot understand why the USA has not approved it for men and women past menopause.

Re: The official Coronavirus thread [Re: 360view] #2787971
06/22/20 07:12 AM
06/22/20 07:12 AM
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Monday’s Wall Street Journal has an article
“Vaccine Efforts Turn to Seniors”
that states that experts are worried that vaccines in development against covid-19 might work for the young, but be much less effective in the elderly that really need them.

There are more than 100 covid vaccines in development,
and 12 presently in the early stages of testing,
so let us hope some will work for older adults.

In influenza vaccines the working dose is increased 3 to 4 times for older adults.
Some vaccines are given with an unrelated chemical called an “adjuvant” to further stimulate the immune system.

https://www.cdc.gov/vaccinesafety/concerns/adjuvants.html

If given prior to a flu vaccine
the herbs ginseng and astragulus seem to work as adjuvants in flu vaccines:

https://pubmed.ncbi.nlm.nih.gov/27597953/

After getting a vaccine, exercising that same day until you are very tired seems to stimulate the immune response and boost the effectiveness of the vaccine.

Re: The official Coronavirus thread [Re: 360view] #2788135
06/22/20 03:35 PM
06/22/20 03:35 PM
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ruxolitinib, a cancer drug, is reported by U of Marburg to significantly help severe covid-19 patients on ventilators

https://medicalxpress.com/news/2020-06-cancer-drug-covid-patient-acute.html

Re: The official Coronavirus thread [Re: 360view] #2788353
06/23/20 08:26 AM
06/23/20 08:26 AM
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Amid all the covid news,
a bit of good news on Cancer;

https://www.bbc.com/news/health-53137328

Sample quote

“This study involved only small numbers of patients...Therefore, it is too early to consider berzosertib a game changer in cancer treatment," said Dr Darius Widera at the University of Reading.
"Nevertheless, the unusually strong effects of berzosertib, especially in combination with conventional chemotherapy, give reasons to be optimistic regarding the outcomes of follow-up studies."
One patient in the trial, with advanced bowel cancer, had his tumours completely disappear after treatment with berzosertib, and has remained cancer-free for two years.
Another, whose ovarian cancer returned following a different course of treatment, saw her tumours shrink after combination treatment with the drug and chemotherapy.
Chemotherapy works by damaging cancer cells' DNA, so using it in conjunction with this new treatment, which stops the cells from repairing themselves, appears to give an even greater benefit.
And berzosertib is able to target tumour cells without affecting other healthy cells, Prof Lord said.
End quote

Re: The official Coronavirus thread [Re: DirectSubjection] #2788370
06/23/20 09:27 AM
06/23/20 09:27 AM
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National decline in covid-19
Deaths per Day
does not match tone of major Media reporting

https://outkick.com/media-ignores-90-coronavirus-death-collapse-in-country/

Note the graphs

96D1FCF2-50C1-4441-AD29-00B1CF8042FF.jpegD4D683AD-238B-4F63-869C-576EFB189856.jpeg
Re: The official Coronavirus thread [Re: 360view] #2788482
06/23/20 02:20 PM
06/23/20 02:20 PM
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Baldness claimed to be a predictor of more severe covid-19.

https://medicalxpress.com/news/2020-06-coronavirus-sex-hormonesbaldness-factor-anti-androgens.html

Sample quote

Another is that men's immune systems are not as good as women's at warding off the severe effects of viral infections.

These factors are indirectly influenced by sex hormones. Now it seems sex hormones might also have a direct effect on SARS-CoV-2's ability to enter our cells and establish infection.

Baldness and COVID-19

In one study of 122 male COVID-19 patients admitted to hospitals in Madrid, 79% were bald—about double the population frequency.

Another small study in Spain observed a similar overrepresentaton of baldness among men hospitalised with COVID-19.

Male pattern baldness is strongly associated with a higher level of dihydrotestosterone (DHT), a more active derivative of testosterone, and one of the androgen family of male sex hormones.

End quote

Re: The official Coronavirus thread [Re: 360view] #2788695
06/24/20 01:21 AM
06/24/20 01:21 AM
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Keep reporting as you have. I read many as I can. Find many very informative.

Re: The official Coronavirus thread [Re: 360view] #2789120
06/25/20 11:01 AM
06/25/20 11:01 AM
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Why children endure covid-19 so much better further studied:

https://medicalxpress.com/news/2020-06-ace2-immune-function-children-severe.html

Sample quote

The way that SARS-CoV-2 virus enters the body and the state of the immune system itself are thought to be two primary differences in how children and adults become infected with coronavirus.

SARS-CoV-2 enters the body by binding to angiotensin converting enzyme-2 (ACE2), which is attached to the outer surface of cells in the lungs, arteries, heart and other organs. Studies have found that expression of ACE2 in the lungs increases with age. Infants and very young children have very low ACE2 expression, and older children have lower expression than adults. Research suggests that children may be protected from the serious respiratory components of COVID-19—including acute respiratory distress syndrome—due to their reduced ACE2 expression.

The immune system also plays a role in infection. Imbalance between mediators that increase versus suppress the inflammatory response plays a critical role in the clinical manifestations of this disease. Heightened immune response is often a factor in the inflammatory "cytokine storm" phase of COVID-19, in which the body attacks itself. Studies have shown that older mice had lower levels of the anti-inflammatory substances IL-10 and IL-13 and higher levels of pro-inflammatory chemicals in the lungs than younger animals.

CD4 T-cells, which play an important role in controlling viral replication and disease severity, are markedly decreased in adults with severe COVID-19.

In addition, lung tissue in children naturally has a higher concentration of regulator T-cells, which may protect against severe COVID-19 by suppressing the immune response that, in adults, may lead to uncontrolled inflammation.

End quote

Re: The official Coronavirus thread [Re: 360view] #2789121
06/25/20 11:07 AM
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A bit weird.
Germans and U of Kentucky researchers looking at whether extracts from wormwood plant and coffee have some beneficial effect against covid-19

https://medicalxpress.com/news/2020-06-annua-sars-cov-.html

Sample quote

A. annua leaves ( wormwood plant) from a cultivated seed line grown by ArtemiLife Inc. in Kentucky, U.S., when extracted with absolute ethanol or distilled water, provided the best antiviral activity. The addition of either ethanolic or aqueous A. annua extracts prior to virus addition resulted in significantly reduced plaque formation. The ethanolic extract of both A. annua and coffee was found to be most active.

However, artemisinin plant (famous as a treatment for Malaria) alone does not present much antiviral activity.

"I was surprised to find that A. annua extracts worked significantly better than pure artemisinin derivatives and that the addition of coffee further enhanced the activity," says Klaus Osterrieder, professor of virology at Freie Universität Berlin who conducted all activity assays.

End quote

Re: The official Coronavirus thread [Re: 360view] #2789124
06/25/20 11:13 AM
06/25/20 11:13 AM
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Flu vaccines not providing much protection to current circulating strains

https://medicalxpress.com/news/2020-06-flu-vaccine-disappointing-strains-season.html

Sample quote

Last winter's flu season featured two waves, each dominated by a different virus. Both flu bugs are considered dangerous to children, and it was a very bad flu season for kids.

Health officials reported 185 U.S. flu deaths in children this past flu season, the second highest total in a decade. And officials believe that because of reporting lags, additional cases may still come in.

Most of the children who died were not vaccinated. But how well the vaccine performs in kids remains a large concern.

A Type B flu strain ended up causing most early season illnesses and the bulk of illnesses in children over the entire winter, Flannery said. The vaccine was about 39% effective against that strain in children.

But the vaccine did an awful job against the Type A H1N1 strain that caused the second wave of illnesses. Protection was so low in kids ages 6 months to 17 years that—statistically speaking—it couldn't be counted as working at all.

The vaccine's performance was down in adults, too, and health officials don't know exactly why. It may be due to changes in the virus, Flannery said.

Health officials have changed the components of what's in the flu shot this year, in what they hope will be a better match against whatever flu strains circulate this fall and winter, he said.

End quote

Re: The official Coronavirus thread [Re: RMCHRGR] #2789277
06/25/20 10:34 PM
06/25/20 10:34 PM
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Originally Posted by RMCHRGR
To be blunt, the ONLY places to rely on for DEFINITIVE information about the COVID-19 virus are the US CDC and The World Health Organization. Anything else is nonsense. Period.

CDC COVID-19

WHO COVID-19

If everyone took a minute to comprehend the gravity of the situation and willingly follows the guidelines recommended by the CDC and WHO to prevent the spread of the virus, we will beat it in short order. If people continue to mistrust that information and ignore the warnings, we will be in for a long, uphill battle.

I for one am not looking forward to being holed up in my house for the next two months.


Wow, I was reread back in the early days of this thread and came across your post here.
Had we heeded early warnings and guidance rather than misguided where would we be today?
It's almost nauseating to think how much time we've lost, how many people we've lost and how much money has been lost. In view of where we are headed I can only shake my head. We were warned and know what needed to be done. I guess masks and a couple months was too much to ask.

Re: The official Coronavirus thread [Re: srt] #2789286
06/25/20 10:50 PM
06/25/20 10:50 PM
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It's interesting, that back when it started we all thought we were going to be in this for only a couple of months, but I suspect it will be much longer.

Aren't some states starting to spike all over again?

Re: The official Coronavirus thread [Re: ChryCoGuy] #2789292
06/25/20 11:11 PM
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I've only tracked Ca and we started by flattening and now it's steady blast-off.

Re: The official Coronavirus thread [Re: 360view] #2789322
06/26/20 01:02 AM
06/26/20 01:02 AM
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Originally Posted by 360view
A bit weird.
Germans and U of Kentucky researchers looking at whether extracts from wormwood plant and coffee have some beneficial effect against covid-19

https://medicalxpress.com/news/2020-06-annua-sars-cov-.html

Sample quote

A. annua leaves ( wormwood plant) from a cultivated seed line grown by ArtemiLife Inc. in Kentucky, U.S., when extracted with absolute ethanol or distilled water, provided the best antiviral activity. The addition of either ethanolic or aqueous A. annua extracts prior to virus addition resulted in significantly reduced plaque formation. The ethanolic extract of both A. annua and coffee was found to be most active.

However, artemisinin plant (famous as a treatment for Malaria) alone does not present much antiviral activity.

"I was surprised to find that A. annua extracts worked significantly better than pure artemisinin derivatives and that the addition of coffee further enhanced the activity," says Klaus Osterrieder, professor of virology at Freie Universität Berlin who conducted all activity assays.
End quote


Good News for Perhaps Coffee Drinkers Out There ??

Re: The official Coronavirus thread [Re: 360view] #2789323
06/26/20 01:05 AM
06/26/20 01:05 AM
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Originally Posted by 360view
Flu vaccines not providing much protection to current circulating strains

https://medicalxpress.com/news/2020-06-flu-vaccine-disappointing-strains-season.html

Sample quote

Last winter's flu season featured two waves, each dominated by a different virus. Both flu bugs are considered dangerous to children, and it was a very bad flu season for kids.

Health officials reported 185 U.S. flu deaths in children this past flu season, the second highest total in a decade. And officials believe that because of reporting lags, additional cases may still come in.

Most of the children who died were not vaccinated. But how well the vaccine performs in kids remains a large concern.

A Type B flu strain ended up causing most early season illnesses and the bulk of illnesses in children over the entire winter, Flannery said. The vaccine was about 39% effective against that strain in children.

But the vaccine did an awful job against the Type A H1N1 strain that caused the second wave of illnesses. Protection was so low in kids ages 6 months to 17 years that—statistically speaking—it couldn't be counted as working at all.

The vaccine's performance was down in adults, too, and health officials don't know exactly why. It may be due to changes in the virus, Flannery said.
Health officials have changed the components of what's in the flu shot this year, in what they hope will be a better match against whatever flu strains circulate this fall and winter, he said.
End quote


Quote
Interesting. Perhaps a precursor to any covid19 that may come about. If this is what happened with the "Normal" flu, what's to become of the current virus. Chilling to think about.

Re: The official Coronavirus thread [Re: srt] #2789342
06/26/20 07:24 AM
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Before blaming the USA on what it should of done early,
do not forget
“What the Chinese Communist Party should have done early.”

SARS back in 2002-2003 should have “educated” the top Chinese.

It is still not well known here in the USA,
but a coronavirus 99.5% similar to covid-19
broke out at a mine in Yunnan Province in 2012,
killed 3 miners,
and sicken dozens.

If the CCP had locked down Hubei Province and Wuhan City when the first dozen deaths happened,
reported the situation to the world,
and began openly testing potential treatments in the lockdown areas in full co-operation with worldwide medical research groups, where would we be now?

Imagine if before covid-19 had spread to the USA, Italy, Iran, etc
it had been known that the cheap drugs
Famotidine,
Dexamethasone
could reduced deaths by
47%
(0.66 times 0.8 equals 0.53)
and that ventilators many times caused more deaths than saved?

Assign the blame to those who denied that a still small fire had even started.

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