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Re: The official Coronavirus thread [Re: pittsburghracer] #2761028
04/07/20 09:52 AM
04/07/20 09:52 AM
Joined: Dec 2007
Posts: 19,745
Puttin' on the foil in Charles...
not_a_charger Offline OP
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not_a_charger  Offline OP
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Puttin' on the foil in Charles...
Originally Posted by pittsburghracer
when you think about it Americans are pretty grubby individuals. One girl I know works at Sams Club. After being there for several years she went to school so she could Be an Audiologist at Sams. Last week she watched a guy lick his fingers three times getting money
out of his wallet to pay. Another girl I know works as a Secretary at a body shop. From where here desk is she can hear whether people use the sink to wash their hands after doing their business. She was shocked to the amount of guys that don’t. Now the idiots are wearing rubber gloves and just throwing them on the ground after removal. Almost as bad as cigarette smokers.


People are gross. Really, really gross. I spent 20 years being inside of other peoples' cars. The way people choose to live is disgusting.


Earning every penny of that moderator paycheck.

DBAP
Re: The official Coronavirus thread [Re: 360view] #2761029
04/07/20 09:52 AM
04/07/20 09:52 AM
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Nasal spray vaccine technique from Iowa/Georgia U looks very promising

https://medicalxpress.com/news/2020-04-successful-mers-vaccine-mice-covid-.html

Sample quote
The study found that just one, relatively low dose of the vaccine given to the mice intranasally (inhaled through the nose) was sufficient to fully protect all the treated mice from a lethal dose of MERS coronavirus.

When the researchers analyzed the immune responses generated by the vaccine, they found that both antibodies and protective T cells were produced. However, the antibody response was quite weak and it seems most likely that the vaccine's protective effect is due to the T cell response in the mouse lungs.

The researchers note several factors that make PIV5 expressing a coronavirus spike protein an appealing platform for vaccine development against emerging coronaviruses. First, PIV5 can infect many different mammals, including humans, without causing disease. PIV5 is also being investigated as a vaccine for other respiratory diseases including respiratory syncytial virus (RSV) and influenza. Second, the fact that a low dose of the vaccine was sufficient to protect the mice might be beneficial for creating enough vaccine for mass immunization. And finally, the vaccine in the current study was the most effective MERS vaccine to date in animal models of the disease.
End quote

Re: The official Coronavirus thread [Re: 360view] #2761032
04/07/20 09:58 AM
04/07/20 09:58 AM
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Germans estimate worldwide there are 20 undetected COVID-19 cases for every one tested.
USA maybe has 50 to 1 undetected.

https://medicalxpress.com/news/2020-04-covid-average-actual-infections-worldwide.html

Re: The official Coronavirus thread [Re: not_a_charger] #2761033
04/07/20 09:59 AM
04/07/20 09:59 AM
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in a cattle trailer down by th...
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Guitar Jones Offline
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Originally Posted by not_a_charger
Originally Posted by pittsburghracer
when you think about it Americans are pretty grubby individuals. One girl I know works at Sams Club. After being there for several years she went to school so she could Be an Audiologist at Sams. Last week she watched a guy lick his fingers three times getting money
out of his wallet to pay. Another girl I know works as a Secretary at a body shop. From where here desk is she can hear whether people use the sink to wash their hands after doing their business. She was shocked to the amount of guys that don’t. Now the idiots are wearing rubber gloves and just throwing them on the ground after removal. Almost as bad as cigarette smokers.


People are gross. Really, really gross. I spent 20 years being inside of other peoples' cars. The way people choose to live is disgusting.

Isn't that the truth. I've worn gloves and put seat covers in cars to protect me. Some cars are the most disgustingly filthy things inside. I may not wash the outside of my old trucks very often but the interior is clean.


"Follow me the wise man said, but he walked behind"


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Re: The official Coronavirus thread [Re: 360view] #2761049
04/07/20 10:35 AM
04/07/20 10:35 AM
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A newly discovered protein human bodies should make called LY6E turns out to be key in the fight against coronavirus infections

https://medicalxpress.com/news/2020-04-animal-coronavirus-defences-route-human.html

Sample quote

When a pathogen attacks, your immune system mounts a two-stage response: an instant, generic one and a slower one tailored to the specific pathogen.

In the first response, cells release interferon—an alert to tissues around the body to produce up to 350 different proteins in the hope that they will halt the virus.

The scientists took advantage of a library of genes built up by American scientists, each of which encodes one of these 350 proteins. When a coronavirus was administered to cells, each of which contained one of these genes, they found that one molecule, LY6E, stood out as far more effective than the others at counteracting it.

They found the same for a number of coronaviruses they tested, including those that cause MERS, SARS (Severe Acute Respiratory Syndrome) and some that cause the common cold.

"I was very surprised to see such a strong effect," said Dr. Stephanie Pfänder, now at Ruhr Universität Bochum, Germany, who worked on the project.

What surprised them more was that, in a mouse model, the coronaviruses specially targeted the cells involved in the body's second, tailored immune response. If these immune cells don't swiftly produce LY6E, the coronavirus wipes them out, destroying the body's chance of launching the second wave of sustained defences against the disease.

"This is a very important molecule," said Prof. Thiel.

"If anybody in our population has a defect in that gene (which codes for it), they might be very vulnerable to infectious diseases."
End quote

Re: The official Coronavirus thread [Re: 360view] #2761064
04/07/20 11:11 AM
04/07/20 11:11 AM
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360view Offline
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Maybe a disease like Measles

https://www.sciencedaily.com/releases/2019/10/191031204630.htm

Is wiping out an older person’s immune system’s ability to fight COVID-19 ?

99% of young people fight COVID pretty well
but older people sometime during their lifetime catch a disease that wipes out the protection they were born with?

Re: The official Coronavirus thread [Re: Guitar Jones] #2761081
04/07/20 12:07 PM
04/07/20 12:07 PM
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Mass
DAYCLONA Offline
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Originally Posted by Guitar Jones

Isn't that the truth. I've worn gloves and put seat covers in cars to protect me. Some cars are the most disgustingly filthy things inside. I may not wash the outside of my old trucks very often but the interior is clean.




In one of my former careers working as a mechanic and autobody tech, the worst vehicles to work on were the ones that people lived in... wanna talk about disgusting filth and a sad view on humanity!

There were times I had to work on vehicles with the "occupants" still inside while making repairs because this was their "home", but when your not the Boss you have no choice, sh!t like this probably wouldn't fly nowadays in a shop because of regulations/liability/insurance guidelines

Mike

Re: The official Coronavirus thread [Re: Runner2go] #2761085
04/07/20 12:24 PM
04/07/20 12:24 PM
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Posts: 3,653
The Historic Hudson Valley
MONC Offline
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Originally Posted by Runner2go
I typed this up in response to a comment about what if the world still only had the ability to text message... no smart phones.

When I went & googled up some SARS research...
I was a little surprised at where it led.. dates & locations right off the SARS wiki page.
No one really knows how many people Chinese just up & disappeared in 03...
----
It is interesting that no new SARS(also Corona) outbreaks occurred after 2004... That is, UNTIL after Chinese "Scientists" finally found the origin bat cave, in remote Yunnan China, in Dec 2017... The bats were then "studied" by scientists from the "Wuhan Institute of Virology" 1000miles away... just 2 short years later... Voila.. an upgraded version of Corona on steroids breaks out in Wuhan, and is blamed on the same horeshoe bats, still living 1000miles away in Yunnan, 😳

Hmmm... work The timing does make you wonder... 13yrs of nothing... Then the bats are found & "studied from 1000+ miles away", & only 2yrs later, an outbreak occurred at the "location of study" Wuhan, & NOT at the location where the bats actually live. 🤔
The world will likely never know what they did inside those boarders... either time. 😔


Read somewhere the facility the scientists were studying the bat virus was in close proximity to the Wuhan wet markets

"“He lives and works at Wuhan’s CDC, a few hundred yards away from the Huanan wet market,” the official said. “He is among the small team in Wuhan that has contributed to China’s obsession in recent years with virus hunting and research.”

Washington Times on line article


Last edited by MONC; 04/07/20 12:27 PM.

Mopar
Or
No
Car
Re: The official Coronavirus thread [Re: hooziewhatsit] #2761115
04/07/20 01:46 PM
04/07/20 01:46 PM
Joined: Jun 2006
Posts: 12,066
(Central) PA
Runner2go Offline
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Originally Posted by hooziewhatsit
Originally Posted by Runner2go

And there is absolutely no evidence it hurts either...


Did you read any or all of that article? Pretty much all of it was saying that there is no true evidence that it helps (yet), and definite evidence that it hurts some people with certain issues, which also makes up most of the people in the ICUs.

Yes... I've also seen other doc's say the opposite and listened to people who recovered via the treatment, say they were happy to receive it.

Just prior to that article coming out, the pharmaceutical company(Novartis) that employ's Derek Lowe (The chemist that wrote the article) committed to donate 130million doses of hydroxychloroquine to whoever needs it, "should it prove effective in treating COVID-19"

Interesting that a company commits to donate it's entire inventory of a certain drug "IF it works" only to have an employee of said company write a blog the very next day claiming it doesn't work...
(thus possibly limiting the chance they have to make good on their pledge)
Timing and intent are everything.... whistling

Something else to keep in mind...
A course of the combo (Plaquenil + Z-pak) everyone is arguing over, can purchased from Walmart pharmacy for a bit over $100 with coupon.
The immunotherapy options we keep hearing about as "more promising", cost a lot more... probably $10-20k work
(Hard to judge price, as many immunotherapy comparatives are mostly cancer related, & run $150k a year and up...)
Funny how only the most expensive options, are always the only "acceptable" winners.... stirthepot

Re: The official Coronavirus thread [Re: 360view] #2761120
04/07/20 01:49 PM
04/07/20 01:49 PM
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Re: The official Coronavirus thread [Re: jcc] #2761151
04/07/20 03:10 PM
04/07/20 03:10 PM
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KY
65pacecar Offline
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Re: The official Coronavirus thread [Re: 65pacecar] #2761171
04/07/20 04:31 PM
04/07/20 04:31 PM
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in a cattle trailer down by th...
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Guitar Jones Offline
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We will probably see a lot of these stories. The elderly that the survive and the healthy young that don't. There is just no way to know who will live and who will die from it. The only sure way to survive it is to not get it.


"Follow me the wise man said, but he walked behind"


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Re: The official Coronavirus thread [Re: Guitar Jones] #2761188
04/07/20 04:58 PM
04/07/20 04:58 PM
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KY
65pacecar Offline
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https://nypost.com/2020/04/06/the-104-year-old-italian-woman-just-kicked-coronavirus-ass/

104 YO has survived both the Spanish Flu in 1918 and the Covid in 2020. Now that is one system that can fight some infection.

Re: The official Coronavirus thread [Re: 65pacecar] #2761190
04/07/20 05:09 PM
04/07/20 05:09 PM
Joined: Jun 2006
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(Central) PA
Runner2go Offline
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Originally Posted by 65pacecar
https://nypost.com/2020/04/06/the-104-year-old-italian-woman-just-kicked-coronavirus-ass/

104 YO has survived both the Spanish Flu in 1918 and the Covid in 2020. Now that is one system that can fight some infection.

thumbs

Re: The official Coronavirus thread [Re: Runner2go] #2761195
04/07/20 05:21 PM
04/07/20 05:21 PM
Joined: Apr 2012
Posts: 1,235
Phoenix, AZ
Jjs72D Offline
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Some people believe this:


All roads lead back to China ..

1. They made a virus for which they already had an antidote.
2. They intentionally spread the virus for financial gain.
3. There is a clear demonstration of efficiency… they have built hospitals within days. They had to be prepared with the organized projects … with the ordering of the equipment,
the hiring of workers, the water and sewage network, the prefabricated building materials and the storage in an impressive volume, it all happened very quickly.
4. They caused chaos in the world, starting with Europe and then the rest of the Western world.
5. They rapidly decimated the economies of dozens of countries.
6. They stopped production and production lines in factories and primary production in tens of countries.
7. They caused the stock markets to collapse and then bought shares, bonds and companies at bargain prices.
8. Then they quickly took control of the epidemic in their country.
9. During all of this, they managed to lower the price of commodities, including the oil price.
10. Now they are going back to mass production while the rest of the world has stopped production.
Also note how quickly Chinese unions took action to ‘hoard' busload purchases in regional shopping centers across Australia, stripping our shelves of toilet paper and staple food.
It happened before most of us knew what was happening, even before we knew what the Corona virus was.

PS: Read the 1999 book by Chinese Colonel Qiao Liang and Wang Xiangsui, "Unrestricted War: China's Master Plan to Destroy America," on Amazon. Everything is there.

Think about this ...

Why are Russia and North Korea almost completely free of Covid-19? Because they are strong allies of China. The lowest reported cases of Covid-19 come from these 2 countries.
On the other hand, South Korea / United Kingdom / Italy / Spain and Asia are seriously affected. And why is Wuhan suddenly free from the deadly virus?

China will say that the initial drastic measures they took were very severe and Wuhan was incarcerated to stem the spread to other areas. I am sure they are using the antidote
to the virus that was already available before they released it.

Why was Beijing not affected at all?

Chinese President Xi Jinping visited Wuhan at the height of the outbreak … he put on a simple RM1 face mask to visit the affected areas? As a president, wouldn’t you have been covered
from head to toe in a suit with hazardous materials? Maybe he didn’t have to worry because the antidote had already been administered?

There is no doubt that this is biological warfare. Maybe this is just phase one …and China is really taking over the world!

Re: The official Coronavirus thread [Re: Jjs72D] #2761208
04/07/20 05:59 PM
04/07/20 05:59 PM
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Guitar Jones Offline
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Well that just blows the whole it's Trump's fault narrative all to hell. laugh2


"Follow me the wise man said, but he walked behind"


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'74 W200 Crew Cab 360, NV4500, D44, D60 and NP205 divorced transfer case. Rear disc and hydroboost coming soon!
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Re: The official Coronavirus thread [Re: Jjs72D] #2761210
04/07/20 06:02 PM
04/07/20 06:02 PM
Joined: Jan 2003
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South Dakota
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https://www.keloland.com/news/capit...rs-but-not-the-one-local-officials-want/


Not sure what you all are going through but aren't you glad our governor isn't governor of some of these other states that are REALLY effected?


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Re: The official Coronavirus thread [Re: Jjs72D] #2761221
04/07/20 06:48 PM
04/07/20 06:48 PM
Joined: Jan 2003
Posts: 15,636
Jefferson State
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srt Online content
ESYC
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Jefferson State
Originally Posted by Jjs72D
Some people believe this:


All roads lead back to China ..
..................................
...........................


What's next war?
I once got a fortune cookie: He who pokes stick sees hornets.
I'm buying stock in Reynolds Aluminum

Re: The official Coronavirus thread [Re: jcc] #2761303
04/07/20 10:53 PM
04/07/20 10:53 PM
Joined: Dec 2003
Posts: 6,704
KY
65pacecar Offline
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KY
John Prine passed from it.

Re: The official Coronavirus thread [Re: 65pacecar] #2761326
04/08/20 12:01 AM
04/08/20 12:01 AM
Joined: Feb 2005
Posts: 20,111
PA.
pittsburghracer Offline
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PA.
Trout fishing season secretly started at 9am Tuesday morning in Pa ahead of schedule. Thousands of fishermen will be lining the streams. Hmmmmm.


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