I use to race at LACR in Palmdale,SO CA , where the density altitude could vary from 4400 Ft in the mornings at 10.00 AM to 7700 Ft in the after noon at 3:00 PM in the summers, not real high though.
We would have to lean the motors down from spring to summer several jets sizes
The track altitude was around 2500 Ft. above sea level. All the Mopar BB I raced and helped tune their like more CFM on the intake side such as going from a 750 CFM carb to a single 1050 Dominator to a six pack and then upwards to a tunnel ram with two 750 or bigger carbs
All of them like more air and fuel like Andy is saying
That was with stock type iron heads, one of my dyno mule motors, 526 C.I. 440 block
with a set of CNC ported Indy 440-1 really like the tunnel ram with two Holley 1050 CFM Dominator carbs. compared to a Indy 440-3 single intake and 1050 CFM Dominator carb.