No one makes the weatherstrip for the factory slider. Haven't seen an NOS one for sale in a very long time. The windshield gaskets suck, they are too small and a total pain in the butt to install. The solid rear window gasket is the same as a Ford part, no lock strip in that. Wing window seals for the 87-93 are also not available and the early window belt weatherstrips are terrible as well. The straight ones. Channel runs are ok but you may find some of the trucks don't have the holes for the pins installed in the run so they have to be removed. The on body door weatherstrips seem to be to thick as the doors don't want to close well. Some are really bad like my crew cab. So bad after replacing one I took it back out, no amount of adjustment could get the door to close.
In short yeah new weatherstrips are nice but the available offerings leave something to be desired. I wouldn't replace any you don't have to.