Yeah It's possible, I wouldn't out trick yourself on the shortblock just a stock stroke 318 with a steel crank, H beams and a good piston. I would try to get more tire under it- at least 28-29" tall and run a 4.56 or 4.88 and I wouldn't run a 'glide- run a th350 with a 8" converter if you are dead set against torqueflites.

I know of a 318 A body with .88's 904 with an 8" and 29" slicks that went 7.80's with 1.88 valve 360 heads,.441" cam performer intake and a TQ, 7.60's with a strip dominator, 7.20's with a strip dominator, EQ magnums with 2.02's and a MP .528 with 1.6 rockers. It ran really well for what it is, it would run mid 1.5 60's leaving off the footbrake at 4k, shift at 6,400 and let it run out the back door, it usually ran 90-91mph but I've seen 93mph once when we had some really good air in Jan.