Generally for a given/desired displacement)modern V8 engines seem to work best (at least in terms of highest average toruqe/broadest overall powerband) with between a .85 and .9 stroke to bore (not bore to stroke which would be the inverse) ratio and at least a ~1.7:1 rod ratio.
Big bore short stroke (like a 327 chevy and 340 mopar) used to be considered the hot ticket but with 40+ years of modern cylinder head technology you don't really have to rely on allieviating bore shrouding to keep the VE up at high piston speeds. Case in point look at the modern LS1 motor
This is over-simplified of course but in general I believe it to be true that this ratio seems to yield be the best balance between adequate torque, wide powerband and optimum power for a ~6500 rpm valvetrain. But as you spin the motor higher with higher compression, better flowing heads and racier valvetrain, generally/ideally the stroke gets proportionally shorter and the rod gets longer.
For every desired torque peak there is also an optimum runner length and cross section, but that goes out hte window whether we're talking Carb, EFI or modern Direct port injection (which doesn't have to carry any fuel in suspension in front of the intake valve. Just as first mass flow and later Direct port injection altered the "rulz", DPI is likely to re-write them yet again because it can alter/vary fuel volume and spray pattern (without vlave interference) as it injects INTO the cylinder.
i would look for Modern DFI and V8's moving to 180 degree crankshafts (to reduce rotating mass and balance intake pulses) to be the next big moves in V8 development. Flat cranks have been inherently low on low/middle RPM torque with carburation but I look to DFI to help offset that in order to take advantage of the better high RPM breathing and lower mass. Another trend once they get this sorted will likely be smaller displacenets (3.5-4.0 litre motors making roughly the same useable power as contemporary 5.0-5.5 litres)
That should be enough to get some debate (but hopefully not
) going!