New 2 drug combo for passing Kidney Stones

Sample quote

The researchers further analyzed their results, looking for a two-drug combination that might be effective at lower, safer dosages. Eventually, they found two top-performing drugs that could produce even more positive results when administered together.

One of the drugs,
nifedipine,
is a calcium channel blocker that doctors can use to treat high blood pressure.
The other is a Rho kinase inhibitor,
which can treat glaucoma.
End quote

Article
https://www.medicalnewstoday.com/articles/327245.php#5

Hope my pee doc reads this. Not really looking forward to the next time even with better drugs. Hope to just avoid them by drinking more water.

I hope this works out the way they think it will. I've only had kidney stone, and that was 2 too many!!! I had to go in and get mine busted because it was too big to pass. I peed a load of gravel a few weeks later...lol. I have also heard that there is a shot in the works to prevent sleep apnea, so people will no longer have to wear CPAP masks.

Interesting. In my case, I'm "calcium-absorptive", meaning I have to keep calcium intake as close to zero as possible.
I asked my kidney surgeon about taking a calcium blocker, but he said not in my case.
(He's not the guy in the office with an interest in Porsches, )
So far, 5 years without dairy, broccoli, green veggies, ice cream, chocolate, tea, etc has kept that issue at bay.
Not always fun - I'd love a good Chicago-style pizza and a salad - but better than the alternative !

Drink your water, kids !

Had em once. Worst pain EVER. Paced the floor all night till the next morning when I could call the nephrologist (kidney doc) across the street. He said the fact that I didn't go to the ER meant it wasn't too bad (NOT BAD?!?!). He said drink a BUNCH of water and you'll pass it. I did. I'm sure I havent been drinking as much water as I should.

20 years earlier a young (late 20's) customer from out of town asked if he could borrow my keys and lay down in the back of my car. I reluctantly said sure. When I went to check on him and hour later I thought he was giving BIRTH. We called an ambulance. This guy used to work for a road construction crew. Said he was holding a tube to place explosives in a hole. Said it exploded and shrapnel caused his arms to swell and the doctors cut the muscles loose before they tore off the tendons. He said that was NOTHING compared to the kidney stones.

I have known a few people that have gone through this, apple cider vinegar and lemon juice is at least one possible home remedy.

If you google it, I am sure you will find some tips.

Went to the ER a couple of years ago with kidney stone pain. Got pain meds and sent home. Back 2 days later. Lather, rinse, repeat. Back 2 days later. Finally, did an MRI and decided it was stuck. They went in with a scope to get it out. I woke up to find out it was septic and too dangerous to attempt removal. I had to be on IV antibiotics for a week before they would try again. Second attempt was successful but I had to deal with a stent and string for another 10 days. I now drink numerous glasses per day of Crystal Lite with potassium citrate. I never want to go through that again.

I've had stones 4 times, haven't had an issue since I started taking magnesium everyday.
That was 10 years ago.

You don't always pass stones if the kidney(s) have them.
In my case, I just woke up one morning and peed blood. I mean blood. No pain.
Called my general Doc, they had me come in immediately, then immediately sent me to the urologist.
Got passed through a machine (MRI?) and it turned out I had what's called a staghorn stone, which had pretty much filled one kidney.
Took 4 procedures to be rid of it: 1st was invasive with tubes, rest were an ultrasound deal & a stent.

I passed about 1 a month for 3 years, the first one I got was tiny and I thought I had the clap from my girlfriend, all I get is a back ache. I pissed something that looked like red coffee in 2006, drove 110 miles to the hospital, gave me a CT scan and I had 5 stones in one kidney, 4 in the other. Largest one was the size of a pea. I did the electroshock lythotrypsy a month later at a hospital that was 380 miles away on one kidney then had to wait 2 months to do the other one. I woke up during the second procedure, that was not fun having the doc holding me down while the nurse pumped me with more drugs to get me back out cold.

2 years later, I was at work on a remote site, I had a percoset that got me through that one, it was the size of a corn kernel. It stopped about half way out, I was drinking water just so I could finish passing it. That was a no underwear day and you dont hold it to pee... The last one I passed was about 2 weeks ago, it was tiny which means that I only get a back ache. The last shocking they did on my kidneys was about 3 years ago. I have to drink about a gallon of water a day and I still get them. Mine are from red meat. High phosphates cause mine. I have passed so many that I have to give women a hard time about giving birth..I just dont understand why they complain...

I had a bunch of stones in my twenties. First 2 urologists just dealt with the symptoms with pain meds and busting them up. Finally found a doc who was interested in finding out the cause. I did a 24 hr. urine study and found the problem. My kidney was not pulling enough citrate out of the urine in the kidney. So now I take 12 pills of potassium citrate/day. 15 yrs later, not a stone since. Moral to the story is find a good doc and get it figured out.

They made me
quit drinking sweet tea !

Never had them, but read they are caused by high levels of sodium and dehydration. People I know who drink alcohol seem to get them more than people I know who don't drink. Drinking alters your body's ability to maintain correct fluid levels.

Never heard that caffeinated drinks actually cause it.

Potassium is your friend. It's stored in your cells and regulates your salt and water levels. You just need to have enough reserve stored away.

It's very easy to blow past the 2000+/-mg of salt you really need in a day. Read the label on soups, chili, etc. and 3000mg a day is more like it. Do this over and over coupled with not enough water and potassium and it's easy to get into trouble.

Avocados turned into guacamole is a great source of potassium, and much better than eating a banana, imo.

Hello All
I have had 4 and any new developments to the passing of those God forsaken things are welcome ! Long live R&D.

They didn't make me....I did it voluntarily! I was 56 before I had a kidney stone attack. My wife and I had just bought our place in Myrtle Beach and were about 2 months into the remodeling. We had worked like dogs all day, and I'm sure I was dehydrated. We went to Outback for dinner that night, and I bet I drank a half gallon of sweet tea! That night, I woke up in horrible pain, and thru up from what felt like somewhere down near my toenails! After I had been to my doctor back home, and then to my urologist....who told me tea (sweet or unsweet) helped form kidney stones. Right then and there I vowed to never drink another drop. He told me it was a lifetime accumulation, and not the 1/2 gallon I drank the night I had the attack. Don't care.....never drinkin another drop!!

amen!

What a bunch of pansies........Just kidding, Over 200 stones either passed or busted up internally. I passed a 17mm stone!!! Doctor said not possible and then I put it on his desk along with the BAG full of many others. I had a jar full that the Wake Forrest Hospital took for study. You need to find out what kind they are and treat accordingly. The Potassium Citrate helped me a lot but I have the Uric Acid stones. 7 Internal procedures over about 2 years including the first two where the doctor said he lost count of them all while laser blasting them internally. I actually walk around most of the time with some. I have a 12 mm one in at the moment good times......

Good Lord Todd! I know you're a big dude.....but it sounds like you got more than your fair share!

Holy smokes....that must be miserable. I have had two. The last one was the one that about put me under. There was NO pain medication that worked. They wanted to send me home until I could not stop throwing up....these things are miserable.

I'm with you Sasquatch - I had me 1st stone at 32 yrs old, 2nd at 41, third at 50 - all 10+mm and passed them all. Now I'm 60 and have an 11mm stone attached to the wall of my left Kidney - good stuff, hate those stents... The pain I had from he one ten years ago caused me to pass out at a graveside funeral service, face down in the snow - that was a good show... LOL (Sorry Mr's D)

you must have Calcium Oxalate stones. There is Oxalate in everything good. Vitamin C is a precursor to it as well. My wife stopped Coca cola (high phosphoric acid content) after three dangerous bouts with stones and 20 years later not one . An acidic urine is bad for some stones but alkaline urine is bad for other types. Glad you are doing better.