Does anyone know if the Milodon #16250 high volume small block water pump is the same as the GMB HP SB water pump (#1201070P). I noticed my Milodon unit has the same "GMB CR07" cast on the inlet as the GMB unit does.

Milodon:
https://www.summitracing.com/parts/mil-16250/overview/make/dodge

GMB:
http://www.rockauto.com/en/moreinfo.php?pk=3096414&cc=1498099&jsn=433

that would convince me that they are the same (same casting for sure with maybe some mods) but w pumps are pretty simple. Just me I think if you got a parts house rebuilt with the most vanes & welded on an anticav plate that your cooling needs would be met (at least as far as the pump goes).

Myself, over the last 40+ or so years have seen ZERO benefit to anything other than a parts store pump on street driven / occasionally race vehicles. Same with water wetter, duralube and other MAGIC fixes. OPPPS,
I just remembered, there was a noticeable difference, My wallet was lighter

My Flowkooler #1700 HiFlow pump has the same casting number on the neck (CR07 GMB).
I think the aftermarket companies use the same base casting but they machine it for their own pump assemblies.

The only one that I know of that is made from a unique casting are the Edelbrock versions. They have a large steel disk with long curved blades that have much more surface area compared to the rest of them. They cost a lot more, but they do work great.

On the water wetter, I've heard that a few drops of liquid dish soap works good.